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High triglycerides correlate strongly with cardiovascular risk, making this improvement clinically meaningful beyond the weight loss itself
Kelsey MM, Geffner ME, Guandalini C et al (2016) Presentation and effectiveness of early treatment of type 2 diabetes in youth: lessons from the TODAY study
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van MeijerenJTimmerIBrandtsHJanssenIBoerH
Of note, in the SURPASS-4 trial, adjudicated major adverse cardiovascular events (MACE) were not increased with tirzepatide compared with insulin glargine over an extended follow-up period of 52 additional weeks after the main trial period of 52 weeks [21]
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