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We do not recommend a low-carb approach for people with certain hormonal conditions or a history of disordered eating without medical guidance, and anyone with a health condition should check with their doctor first

Patients using semaglutide report significantly reduced hunger throughout the day, feeling full more quickly during meals, decreased cravings for calorie-dense foods, increased physical activity energy levels, and visible improvements in blood sugar, cholesterol, and blood pressure levels

If gastrointestinal symptoms significantly impair quality of life or prevent medication adherence despite conservative management, healthcare providers may consider dose adjustment, alternative agents with potentially different side effect profiles, or referral to a gastroenterologist for specialized evaluation

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GLP-1 receptor agonists like semaglutide and tirzepatide suppress appetite by increasing feelings of fullness, which can make eating adequate protein challenging for patients on active therapy