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64,65 Cytokine agents such as the CD122 agonist bempegaldesleukin have demonstrated immune-expanding activity in phase I-II trials and restored antitumor responses in B2M-null models when combined with PD-1 blockade in preclinical settings
Dawson TM, Dawson VL
Cancer 16, 843848
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Lifestyle factors like smoking, alcohol consumption, stress, and poor diet can reduce glutathione levels in the body, thereby affecting the longevity of the treatment effects
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