Deschler S, Kager J, Erber J, Fricke L, Koyumdzhieva P, Georgieva A, et al
Further, clinicians have only recently begun to consider the unique advantages of nasal administration, spurring the development of pharmaceuticals that are highly bioavailable via the nasal mucosa
J Skorodok, St Petersburg
The 500 mcg per-capsule dose mirrors the per-day intake used in the bulk of rodent oral studies, and the gastric origin of the parent molecule provides a biological rationale for stability through the GI tract a feature documented across multiple oral-administration preclinical models
In our review, some ( Patients with vitamin B12 deficiency who are symptomatic have severe neurological deficits or have critically low blood levels of vitamin B12 should be treated with IM administration