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Having food in your stomach provides a buffer against nausea, while keeping the meal light prevents the excessive fullness sensation that higher doses can trigger
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Invest New Drugs 38 (1), 5059
A 2016 study of Expert Review of Respiratory Medicine concluded that doses of NAC greater than 1,200 mg per day could help prevent acute exacerbations in those with COPD, which is important as many with chronic lung disease end up in hospitals during an acute attack
These are often the reason why patients stop taking the medication
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