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On the other hand, insulin is a potent stimulant of lipid synthesis, antagonising TG breakdown

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Collagen type I is particularly important because it forms the backbone of the extracellular matrix, supporting dermal strength and elasticity

Amylin, a neuroendocrine hormone co-released with insulin, controls hunger, gastric motility, glucagon secretion, and energy metabolism via divergent amylin receptor (AMYR) subtypes (1-3), namely the calcitonin receptor (CTR) and the receptor activity-modifying proteins (RAMPs)