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Psoriasis has been known to be a common chronic inflammatory skin disorder (Lerman et al
GI symptom rates at the 12 mg dose included nausea (38-43%), diarrhea (33-35%), constipation (21-25%), and vomiting (20-21%)
Certain medications can contribute to leg cramps, including loop and thiazide diuretics, beta-agonists, and statins (which more commonly cause diffuse myalgia rather than focal cramps)
And listen to the problem one FDA official laid out at that meeting
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