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A 12 mg retatrutide vial with 3 mL of bacteriostatic water makes 4 mg/mL, where 2 mg draws 50 units and 4 mg draws 100 units

Sci Transl Med 3(77)

Male or female, aged 18 years at the time of signing informed consent

Early-phase clinical trial data, including results from a Phase 2 randomised controlled trial published in The New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023), demonstrated significant weight reduction in adults with obesity (without type 2 diabetes), with participants receiving the highest dose losing a mean of approximately 24% of their body weight over 48 weeks