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For calculations of peptide intensity differences and associations with beta cell function, a false discovery rate (FDR) of 0.05 was applied after multiple hypothesis correction using the BenjaminiHochberg procedure
About this article Cite this article Fisman, E.Z., Tenenbaum, A
Combining eight studies that reported voiding ability after cystoplasty, 103 of 144 patients (72%) voided spontaneously without the need for intermittent catheterization
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This comparative perspective juxtaposes the two compounds with respect to molecular pharmacology, clinical efficacy, safety, and potential clinical positioning, and proposes that, because resmetirom primarily targets hepatic lipid disposal whereas semaglutide unloads systemic caloric pressure, their complementary actions could be harnessed sequentially or in combination to achieve broader, more durable disease modification across the heterogeneous spectrum of patients with MASH
