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Gene expression data (human): Even without long-term outcomes data, human scalp studies show that topical GHK-Cu activates genes involved in follicle cycling within weeks of application

However, another randomized, double-blind, placebo-controlled trial in 181 patients with diabetic neuropathy found that oral supplementation with either 600 mg/day, 1,200 mg/day, or 1,800 mg/day of lipoic acid for five weeks significantly improved neuropathic symptoms (77)

These typically resolve on their own or by temporarily reducing the dose

But I think the most, one of the biggest things you said there was making sure its FDA approved and such

The weekly break is a small-scale version of the same idea