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No head-to-head Phase 3 data between retatrutide and tirzepatide was available at the time of the TRIUMPH-4 readout
Generally, these medications are intended for long-term use to maintain weight loss and manage conditions like type 2 diabetes
The subsequent downstream signaling cascade initiated from substrates of the insulin receptor activates kinases and transcription factors vital in promoting cell metabolism, neuronal growth and differentiation, gene transcription, synaptic plasticity, and neuroprotection [133] (Fig
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Methods: The study sample comprised 993 adults (Females 68%)
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