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doi:10.1136/bmj.1.5853.587
Ferritinophagy is involved in iron-overloaded EMFF-induced ferroptosis in granulosa cells To further explore the mechanism of ferroptosis in granulosa cells induced by iron-overloaded EMFF, we studied clinical samples and examined the indicators of iron metabolism and ferroptosis in EMFF and granulosa cells from patients with EMs-related infertility
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When we rank-ordered host genes by their median robust z-scores (measure of deviations from the median), we found a wide range of genes for which Cas9-assisted knockout either reduced or promoted parasite growth, parasite development, or actin recruitment to parasite vacuoles (Figs 1B-D)
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