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5.1.2 Non-enzymatic antioxidants The human bodys non-enzymatic antioxidant system is made up of low-weight antioxidant compounds such as coenzyme Q10, lipoic acid, melatonin, and bilirubin, as well as antioxidant proteins (metal binding) like albumin, lactoferrin, ceruplasmin, ferritin, transferrin, and metallothioneins

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It is not strictly unexplored, nor is it a failed target

Diabetes (2011) 60(4):124657.10.2337/db10-1338 128 ShimasakiTMasakiTMitsutomiKUenoDGotohKChibaSet alThe dipeptidyl peptidase-4 inhibitor des-fluoro-sitagliptin regulates brown adipose tissue uncoupling protein levels in mice with diet-induced obesity

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