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Cell Rep 21(5):11601168
It is important to mention that obesity is a significant risk factor related to several leading causes of death in the United States including: heart disease, cancer, type 2 diabetes, and hypertension, all of which decrease quality of life and life expectancy
In the NAFLD substudy, more than 85% of participants on the highest dose achieved complete normalization of liver fat
By activating GLP-1 receptors, natural GLP-1 and GLP-1RAs reduce insulin resistance, suppress neuroinflammation and oxidative stress, and prevent negative changes in neuroplasticity
As a glucagon-like peptide-1 (GLP-1) receptor agonist, semaglutide enhances the bodys natural mechanisms for appetite control and energy metabolism
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