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2010 Jan 12;3(1):125-145

To PEGylate or not to PEGylate: immunological properties of nanomedicines most popular component, polyethylene glycol and its alternatives

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In skin specifically, GHK-Cu has been extensively studied for its ability to increase collagen and elastin production, improve skin thickness and elasticity, reduce fine lines and wrinkles, improve skin firmness, reduce photodamage, reduce hyperpigmentation, and accelerate wound healing