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Initial small trials from 2016 to 2017, including EXSCEL, FIGHT, and LIVE, were not supportive of the use of GLP-1RAs in HFrEF with negative outcomes related to cardiovascular events [53,54,55]
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Fad diets and excessive exercise may lead to temporary weight loss but often do not offer a long-term solution for chronic weight management
This dual approach has demonstrated greater weight loss outcomes in clinical trials
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