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10.1053/j.ajkd.2024.11.013 Am J Kidney Dis

Specifications Retatrutide is a synthetic peptide engineered as a balanced agonist at three metabolic receptors simultaneously: GIP, GLP-1, and glucagon

When high heterogeneity was detected, subgroup and sensitivity analyses were conducted to explore its sources

Those with inflammatory bowel disease, including Crohn's disease or ulcerative colitis, may experience symptom exacerbation, though evidence remains mixed regarding causation versus coincidence