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Applications in Animal Aging Models Animal aging models (such as naturally aged mice, D-galactose-induced aging mice, SAMP8 accelerated senescence mice, etc.) are core carriers for simulating human aging and verifying the efficacy of anti-aging drugs
Additionally, the ethyl linker extends into the Q2 pocket, allowing the thiazol-5-yl methyl benzimidazole motif of 1 to form a hydrogen bond with Y693
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