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Yes, weeks six through eight can be uncomfortable, but the vast majority of users find it entirely tolerable with basic management strategies: eating smaller meals, favoring cold foods over hot, staying hydrated, and timing injections before rest days
The Cochrane Database of Systematic Reviews, 2016 (3), CD007435
[2] DPP-4 inhibitors (such as sitagliptin or linagliptin) enhance the body's own GLP-1 levels by preventing its breakdown, though they are less potent than GLP-1 agonists for glucose control and weight loss
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