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(PMID: 15531385), rats given BPC-157 0.0045 mg/lb showed significantly elevated serotonin synthesis in the substantia nigra reticulata and medial anterior olfactory nucleus following acute administration

While spirulina offers other nutrients, it cannot support B12 levels and should not be used as a B12 source, especially for those who follow plant-based diets or are already deficient

The peptide also demonstrates rapid desensitization, losing effectiveness within weeks of continuous use

See our TB-500 guide for the underlying research

It is interesting, however, that evaluation of small fiber function as performed by QST (that is, thermal thresholds) did not show significant changes following ARA 290 administration