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Sanadi RM, Deshmukh RS
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The difference in free energy, of electron flow through complexes I and II, accounts for the fact that a pair of electrons originating from NADH and passing to oxygen supports production of 2.5 (more commonly reported as 3) equivalents of ATP, while two electrons from FADH 2 (at complex II) support the production of only 1.5 (more commonly reported as 2) equivalents of ATP
However, the genetic determinants of ferroptosis in RCC cells remain unknown, and further studies are needed
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