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An observational study published in 2023 in Diabetes Care that looked to determine whether the use of GLP-1 medications was associated with an increased risk of thyroid cancer found that in 1-3 years of treatment, the risk for thyroid cancer was increased for those taking GLP-1 medications (2)
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It was developed in the 1990s, gained FDA approval in 2005 for type 1 and insulin-treated type 2 diabetes research and clinical use, and demonstrated that amylin signaling could be safely engaged in clinical research populations
