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One of the organs that may be most affected by this deficiency is the brain, as this organ has a high respiratory rate and is prone to oxidative stress [344]

To evaluate potential publication bias in the meta-analysis, the linear regression test for funnel plot asymmetry (Eggers test) was performed, with the standard error as the predictor and inverse variance as the weight, accounting for multiplicative residual heterogeneity ( 2 = 7.220)

doi: 10.3389/fimmu.2025.1570333 349

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