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Likewise, BPC 157 ameliorates healing and recovers the impaired function of severely injured muscles that otherwise fail to spontaneously heal and plays a role after complete transection, crush, and denervation injuries [77,78,79,80] and after succinylcholine intramuscular application, muscle lesion, neuromuscular junction failure, fasciculations, paralysis, and hyperalgesia [81]

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It is unproven whether BPC-157 causes receptor downregulation in humans

This is the same logic that makes the sildenafil-nitrate combination contraindicated: the FDA label for Viagra states that "administration of Viagra to patients who are using organic nitrates in any form is contraindicated" because of "potentiation of the hypotensive effects of nitrates" [3]

Steroids provide short-term relief but are toxic to tendons, ligaments, and cartilage with repeated use