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Decisions about semaglutide, tirzepatide, dosing, and monitoring should be made with a qualified clinician who can review your full medical profile and provide individualized recommendations
Now used for obesity treatment without diabetes, GLP-1 receptor agonists are available in various forms, including injectable options like exenatide extended-release
Absolute contraindications Cardiovascular disease
Retatrutide has not received MHRA or EMA marketing authorisation and is not currently available as a licensed treatment in the UK
To minimise these effects, take metformin with or immediately after meals, and consider extended-release formulations if standard metformin causes significant digestive upset
