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This was notably not due to any new safety concerns and may potentially be driven by the manufacturers reluctance to introduce a black triangle to ensure clinician and patient awareness of the increased monitoring requirements in type 1 diabetes [29]
In contrast, in in vivo assay, xCT-KO pancreatic ductal adenocarcinoma (PDAC) cells injected subcutaneously managed to form a tumor, although with a short delay
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