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The large-scale STEP clinical trials (Semaglutide Treatment Effect in People with Obesity), published in the New England Journal of Medicine and JAMA, did not report increased cold sensitivity as a significant adverse effect
Adjusting the Normal Dose of B12 Injection for Severe Cases For severe vitamin B12 deficiency, higher doses might be needed to quickly fill up body stores
The statistical analysis was performed using SPSS version 12.0 software (SPSS Inc., Chicago, IL, USA)
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