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3.5 Apoptosis regulation 3.5.1 Apoptosis promotion Ultraviolet radiation disrupts epidermal homeostasis by concurrently activating pro-apoptotic pathways (e.g., p53/Bax upregulation, p38 MAPK activation) and pro-survival signals (e.g., COX-2-mediated proliferation) (Mlitz et al., 2016
References Salvador R, Moutinho CG, Sousa C, Vinha AF, Carvalho M, Matos C (2025) Semaglutide as a GLP-1 Agonist: A Breakthrough in Obesity Treatment
Partnering with Novo Nordisk allows us to apply our platform across important metabolic disease areas, with the goal of enabling oral therapies that would otherwise require injection. Last month, Roche shared positive news on the advancement of its own injectable GLP-1/GIP receptor agonist candidate in obesity
Similar content being viewed by others Introduction Weight loss can arise in a variety of clinical contexts, including chronic diseases such as anorexia nervosa and inflammatory bowel disease, as well as from active medical interventions like bariatric surgery and pharmacotherapy
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