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The absolute risk increase for diabetic retinopathy complications was greater among patients with a history of diabetic retinopathy at baseline (semaglutide 8.2%, placebo 5.2%) than among patients without a known history of diabetic retinopathy (semaglutide 0.7%, placebo 0.4%)
So, it may take several years for the anemia to develop after absorption of the vitamin has stopped
Start with lower concentrations and frequency
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Missed or late doses increase reaction risk, and erratic timing can lead to more pain or swelling
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