Future investigations employing sequential single-cell transcriptomics, specific inducible gene knockouts, and clinical cohort stratification are urgently needed to elucidate these temporal dependencies, which will pave the way for precise, stage-targeted RCD-modulating therapies in DKD
In the group that compared SGLT2i to metformin, the HbA1c, weight, and FPG estimates had low certainty because of the unclear selection bias results and wide confidence intervals in the two studies, as shown in Supplementary Table 7B
The accumulation of unstable iron (LPI and LCI) and NTBI will inevitably lead to excessive iron deposition in tissues and organs, ultimately causing multiple target organ damage, seriously affecting the quality of life and survival time of patients
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Gastric Cancer (2020) 23:24159