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Interestingly, metformin continues to hold its ground in this evolving therapeutic landscape towards wider access to GLP-RAs, as a potential anchor of the GLP-1 RA care journey

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For instance, topical or intrauterine delivery of growth-promoting peptides has been trialed in other tissues

The prolonged gastric emptying further supports sustained postprandial fullness, a mechanism especially helpful for patients who struggle with frequent snacking or binge eating patterns

Study approval For human data, written informed consent was obtained from all patients, and the study was approved by the responsible Ethical Committee of Istituto Ortopedico Rizzoli (protocol no