Mounjaro and Zepbound are brand names for a drug called tirzepitide, which mimics the effects of GLP-1 and another hormone called glucose-dependent insulinotropic polypeptide (GIP)
How well it works depends on things like where your metabolic health is starting from, your nutrition and activity habits, and how consistently you take the medication
That distribution overlaps almost exactly with the circuits implicated in neurodegeneration, addiction, and mood disorders, which is why neuroscientists began paying attention
Hanney SR, Castle-Clarke S, Grant J, et al
Background and aims: Retatrutide (RETA), an agonist of GIP, GLP-1 and glucagon receptors, significantly reduced HbA1c up to 2.2% (0.5 mmol/mol) and body weight up to 17% at 36 weeks in a Phase 2 trial in participants with Type 2 diabetes (T2D)