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These inherent constraints preclude causal inference between GLP-1 RAs and NAEs while preventing incidence rate calculations 75
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GLP-1Rs are distributed across the CNS, notably in areas critical for the regulation of food intake and body weight, such as the Arc and the PVN
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The main friction is the $250 first-visit fee (subsequent visits $150) and the hard Medicare/Medicaid exclusion, which cannot be worked around on the public funnel
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