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Potency and PK anchors: Lau 2015 (cAMP EC50 6.2 pmol/L), Boianelli 2024 (free fraction 0.36%), FDA 2021 (weight-change EC50 54.6 nmol/L)
There was never changes
Anetta Reszko
For instance, most empirical evidence is derived from animal models, such as mice and boars, whereas studies using human clinical samples remain limited
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