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An early GLP-1 drug, Exendin-4, was found to reduce conditioned place preference and dopamine release in the nucleus accumbens in response to nicotine, cocaine, and amphetamine (a brain region that is understood to play a crucial role in the bodys reward system) as well as to reduce cocaine self-administration and seeking behavior in rats

References FDA Label for Wegovy (Semaglutide) FDA Label for Adipex-P (Phentermine) STEP Clinical Trial NEJM Phentermine Efficacy & Safety Review Disclaimer: This article is for educational purposes only

Always discuss any new supplements or sleep medications with your PlexusDx provider first

MOTS-C does it directly, by suppressing TNF-alpha, IL-6, and IL-1 beta at the cellular level

If nighttime dryness improves but daytime symptoms persist, add more frequent sipping intervals or a daytime oral spray