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I don't think we can make a generalized overview on how effective the malic acid component was in the Citrulline Malate research either because we can't determine if the results were derived from the malic acid, the L-Citrulline, or both

Ozempic (Injection) Indication : Type 2 Diabetes, cardiovascular risk reduction Frequency : Weekly Wegovy (Injection) Indication : Chronic weight management (obesity or overweight with comorbidities) Frequency : Weekly Rybelsus (Tablet) Indication : Type 2 Diabetes

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10.1016/j.contraception.2007.01.025 89 MatsuoH

This is why subcutaneous delivery is at the moment the only feasible route for all GLP-1 receptor agonists