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Mean treatment duration was 39 weeks, with a range of 11 to 176
Additionally, glutaminase (GLS), which metabolizes glutamine to glutamate, is a NRF2 target gene [74]
Large epithelioid (type A) melanocytes tend to dominate in the superficial dermis ( Fig
Immune cells, such as macrophages, are recruited to the site of tumor growth, and their activity further increases ROS production, contributing to a positive feedback loop that sustains inflammation and supports melanoma cell survival 71
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