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They further note that, given peripherally, BPC 157 counteracts central dopamine-system disturbances and induces serotonin release in the substantia nigra, and that it can heal various wounds and instantly recover disturbed lower esophageal and pyloric sphincter pressure in rats with long-standing esophagitis
This creates a dependency dynamic where continued use is necessary to maintain results
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The week-72 steady-state mean in the obese cohort was about +0.6 to +2.6 bpm across doses. During escalation around weeks 16 to 20, the peak ran two to three times higher
