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However, human data remained mixed, leaving a gap between preclinical fears and clinical reality
Others are hesitant about injectables , evidenced in the anticipation around Eli Lillys oral candidate, orforglipron
However, dose-dependent gastrointestinal effects limit efficacy, so drugs with GLP-1 and GCG pharmacology can also target alternative pathways and may expand the therapeutic index (132)
People deficient in vitamin B12 may only experience some of these symptoms or a few in combination
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