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Among the children with ASD, nine were diagnosed with comorbid neuropsychiatric conditions, including attention deficit hyperactivity disorder (ADHD) (n = 6), adjustment disorder with tic disorder (n = 1), obsessivecompulsive disorder (n = 1), and learning deficits (n = 1)

Sleep, 41(1)

Res 3 , 9498 (2015)

2018;65:e12498

Finally, the fermentation was scaled up in a 5-L fermentor, and the highest titer and yield were improved to 5680 mg/L and 45.13 mg/g, respectively, by optimizing the addition conditions of amino acids (40 mM added after 40 h)