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First of all, the pathogenesis of obesity was multi-factorial and not completely understood, like the genetic factors, different diet and exercise habits, induced by other diseases such as polycystic, et al

Mice were randomized based on body weight, then treated with either vehicle or mGIPR-Ab/P1 peptideantibody conjugate every 6 days for 18 days

The discrepancy was reduced when restricting to the 195 participants with both survey and EHR data, but remained significant (self-report = 14.14% versus 8.43% in EHR, P = 1.1 10 9 paired t -test

Clinical trials show patients achieve 15-22% weight loss while lowering HbA1c by 1-2%, often reducing or eliminating other diabetes medications

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