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CagriSema Storage & Handling Storage Reference Lyophilized (powder form) Cagrilintide -4F (-20C) long-term Semaglutide -4F (-20C) long-term Pre-blended CagriSema -4F (-20C) long-term Reconstituted (liquid form) Cagrilintide 35.646.4F (28C) Semaglutide 35.646.4F (28C) Pre-blended CagriSema 35.646.4F (28C) Appearance Cagrilintide Clear after reconstitution Semaglutide Clear after reconstitution Pre-blended CagriSema Clear after reconstitution Stability window after reconstitution Cagrilintide Up to ~28 days refrigerated Semaglutide Up to ~28 days refrigerated Pre-blended CagriSema Per supplier COA Always defer to the supplier's specific stability window
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Blood-brain barrier The concept of the BBB can be traced back to the finding by Humphrey Ridley in 1695 [1, 2]
For general safety background, refer to CDC Safe Injection Practices
2 3 Interestingly, in patients with type-2 diabetes, some studies showed GLP-1 analogs to lower glucose levels and HbA1c without affecting the patients insulin or C-peptide levels
