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13 GengY.ChenY.SunW.GuY.ZhangY.LiM.et al (2020)

FIGURE 2 The primary ROS produced by the ETC is superoxide, a free radical with moderate reactivity, whose generation can lead to more reactive or secondary ROS derivatives

The disruption of the gut RvD5n-3 DPA-IL-10 axis is a key mechanism by which P.g weakens the gut barrier and permits its arthritogenic actions ( P.g also exacerbates inflammatory bowel disease (IBD) by directly degrading the tight junction protein ZO-1 via its gingipains, and by altering gut microbiota to expand IL-9-producing CD4+ T cells, which drive intestinal inflammation (Tsuzuno et al., 2021

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Health Benefits and What to Expect How Does Glutathione Help Lighten Skin