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UK Prospective Diabetes Study (UKPDS) Group (1998) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
Human Trx and GSH systems have compensatory activities so that inhibition of one arm can be supplemented by the other 60 , suggesting that the inhibition of hTrxR by some of the compounds presented here will not be detrimental for humans as it is for schistosomes
E., Saelim, M., et al
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This advantage is attributed, in part, to fasting-induced elevations in GH, which stimulate lipolysis and limit proteolysis during energy deficit periods [21]
