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PIONEER 9 and 10 only included patients from Japan that had a lower average body weight, were mostly male (68% to 83% of patients) and were on a combination of background therapies that is atypical for patients living in Canada (high use of TZD and Alpha-glucosidase inhibitor in PIONEER 10)
Missing doses disrupts the steady-state blood levels that weekly dosing creates
Here are some tips: Store in a Cool, Dry Place: Medications should be kept in a cool, dry location away from direct sunlight
A small number of patients reported headache and general malaise
How important are before-and-after photos for Mounjaro
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