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The improvement in lipid metabolism and immune function was further confirmed in companion publications by the same research group, which showed connections between global DNA methylation and its effect on proliferator-activated receptor alpha (PPAR) (Osorio et al., 2016)
Risk stratification and monitoring are important components of NAFLD care
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription
10.1161/ATVBAHA.119.313200 Arterioscler Thromb Vasc Biol
Inhibition of the Xc- transport system by genetic (siRNA, CRISPR) or pharmacological means (Erastin, Sulfasalazine) impairs cystine transport and GSH synthesis, leading to the inactivation of GPX4 and induction of ferroptosis [14]
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