Reda A, Veys K, Kadam P, Taranta A, Rega LR, Goffredo BM, Camps C, Besouw M, Cyr D, Albersen M, Spiessens C, de Wever L, Hamer R, Janssen MCH, DHauwers K, Wetzels A, Monnens L, van den Heuvel L, Goossens E, Levtchenko E (2021) Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood-testis barrier and a subtherapeutic effect of cysteamine in testis
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Nat Med 9(9):11731179
The events manifested soon after the initiation of GLP-1 RA treatment, with a median onset time of 92 days (range: 03,312, n = 1,591) across all ICSRs that provided both drug initiation and AP onset times
In brain microvessels, the activation of AT 1 -R is associated with imbalance in vascular tone regulators together with vascular leakage and inflammatory cell recruitment (Yamakawa et al., 2003