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More recently, tirzepatide a synthetic 39-amino-acid peptide that dual-agonizes GLP-1 and GIP receptors was approved as Mounjaro (diabetes, 2022) and Zepbound (obesity, 2023)
Dynamic imaging of LDH inhibition in tumors reveals rapid in vivo metabolic rewiring and vulnerability to combination therapy
doi: 10.1016/j.pcad.2016.05.002 123
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Journal of Applied Physiology, 109(3), 711718
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