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Administration of oxytocin nasal spray resulted in an increase in oxytocin plasma levels from 20.8 5.9 pg/mL at baseline to 41.1 19.9 pg/mL after 15 minutes (P=.02) and 35.1 16.4 pg/mL after 30 minutes (P=.07)

55 In a broad sense, these findings suggest that effects of GIP on cardiac remodeling may differ based on the ambient pathophysiologic milieu

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This raises major concerns about safety, dosing, and quality control