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Early research suggests greater fat loss and less rebound weight gain compared to semaglutide in animal studies
In summary, long-acting GLP-1R agonists primarily reach the circumventricular organs of the hindbrain and food-intake controlling centers of the hypothalamus
That's a clinically meaningful result - it's larger than what any prior obesity pharmacotherapy had achieved at scale
Genomics: A Gut Prediction
In 2025, before the Wegovy pill was approved, the Wegovy injection was approved for treating the liver disease metabolic-associated steatotic hepatitis (MASH)
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